CHEK2 gene homepage

General information
Gene symbol CHEK2
Gene name checkpoint kinase 2
Chromosome 22
Chromosomal band q12.1
Imprinted Unknown
Genomic reference NG_008150.2
Transcript reference NM_001005735.1, NM_001257387.1, NM_007194.3, NM_145862.2
Associated with diseases BrCa, PrCa
Citation reference(s) -
Curators (1) Despoina Kalfakakou
Total number of public variants reported 253
Unique public DNA variants reported 73
Individuals with public variants 291
Hidden variants 0
Date created May 20, 2020
Date last updated June 26, 2020
Version CHEK2:200626

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 16627
Entrez Gene 11200
PubMed articles CHEK2
OMIM - Gene 604373
OMIM - Diseases BrCa (Breast Cancer)
PrCa (Prostate cancer)


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000035 22 transcript variant 1 NM_007194.3 NP_009125.1 253
00000036 22 transcript variant 2 NM_145862.2 NP_665861.1 253
00000037 22 transcript variant 3 NM_001005735.1 NP_001005735.1 253
00000038 22 transcript variant 4 NM_001257387.1 NP_001244316.1 253


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