Graphs & statistics on gene MSH2

Variant type (DNA level, all public variants)
All public variants (367)
Unknown
Deletions
Duplications
Insertions
Substitutions
Deletions
8%
Substitutions
88%

 
Unique public variants (108)
Unknown
complex
Deletions
Duplications
Insertions
Substitutions
Deletions
6%
Substitutions
89%

 
Variant type (DNA level, all public pathogenic variants)
All public pathogenic variants (43)
Unknown
Deletions
Duplications
Substitutions
Unknown
7%
Deletions
47%
Substitutions
42%

 
Unique public pathogenic variants (17)
Unknown
complex
Deletions
Duplications
Substitutions
Unknown
6%
complex
12%
Deletions
18%
Duplications
6%
Substitutions
59%

 
Variant type (Protein level, all public variants) (note: numbers are sums for all transcripts of this gene)
All public variants (733)
Unknown
Frameshifts
In frame deletions
Missense changes
Silent changes
Stop changes
Missense changes
21%
Silent changes
67%

 
Unique public variants (109)
Unknown
Frameshifts
In frame deletions
Missense changes
Silent changes
Stop changes
Frameshifts
6%
Missense changes
72%
Stop changes
15%

 
Variant type (Protein level, all public pathogenic variants) (note: numbers are sums for all transcripts of this gene)
All public pathogenic variants (85)
Unknown
Frameshifts
In frame deletions
Missense changes
Stop changes
Unknown
25%
Frameshifts
21%
In frame deletions
12%
Missense changes
9%
Stop changes
33%

 
Unique public pathogenic variants (31)
Unknown
Frameshifts
In frame deletions
Missense changes
Stop changes
Frameshifts
23%
In frame deletions
10%
Missense changes
13%
Stop changes
52%

 
Variant location (DNA level, all public variants) (note: numbers are sums for all transcripts of this gene)
All public variants (733)
Unknown
3'UTR
5'UTR
Coding
Intron
Splice region
Coding
64%
Intron
32%

 
Unique public variants (108)
Unknown
3'UTR
5'UTR
Coding
Intron
Splice region
Coding
62%
Intron
31%

 
Variant type (DNA level, all public pathogenic variants) (note: numbers are sums for all transcripts of this gene)
All public pathogenic variants (85)
Unknown
Coding
Unknown
19%
Coding
81%

 
Unique public pathogenic variants (17)
Unknown
Coding
Unknown
12%
Coding
88%