MSH6 gene homepage

General information
Gene symbol MSH6
Gene name mutS homolog 6
Chromosome 2
Chromosomal band p16.3
Imprinted Unknown
Genomic reference LRG_219
Transcript reference NM_000179.2, NM_001281492.1, NM_001281493.1, NM_001281494.1
Associated with diseases ENC, HNPCC5, MMRCS
Citation reference(s) -
Curators (1) Despoina Kalfakakou
Total number of public variants reported 383
Unique public DNA variants reported 111
Individuals with public variants 433
Hidden variants 0
Date created May 20, 2020
Date last updated November 23, 2020
Version MSH6:201123

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 7329
Entrez Gene 2956
PubMed articles MSH6
OMIM - Gene 600678
OMIM - Diseases ENC (Endometrial cancer, familial)
HNPCC5 (Colorectal cancer, hereditary nonpolyposis, type 5)
MMRCS (Mismatch repair cancer syndrome)


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000131 2 mutS homolog 6 (E. coli), transcript variant 1 NM_000179.2 NP_000170.1 383
00000132 2 mutS homolog 6 (E. coli), transcript variant 2 NM_001281492.1 NP_001268421.1 383
00000133 2 mutS homolog 6 (E. coli), transcript variant 3 NM_001281493.1 NP_001268422.1 383
00000134 2 mutS homolog 6 (E. coli), transcript variant 4 NM_001281494.1 NP_001268423.1 383


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2020-2024. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.