TP53 gene homepage

General information
Gene symbol TP53
Gene name tumor protein p53
Chromosome 17
Chromosomal band p13.1
Imprinted Unknown
Genomic reference LRG_321
Transcript reference NM_000546.5, NM_001126112.2, NM_001126113.2, NM_001126114.2, NM_001126115.1, NM_001126116.1, NM_001126117.1, NM_001126118.1, NM_001276695.1, NM_001276696.1, NM_001276697.1, NM_001276698.1, NM_001276699.1, NM_001276760.1, NM_001276761.1
Associated with diseases ADCC, BCC7, BMFS5, BrCa, CPP, CRC, GLM1, LFS, OSRC
Citation reference(s) -
Curators (1) Despoina Kalfakakou
Total number of public variants reported 134
Unique public DNA variants reported 47
Individuals with public variants 159
Hidden variants 0
Date created May 20, 2020
Date last updated September 17, 2020
Version TP53:200917

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 11998
Entrez Gene 7157
PubMed articles TP53
OMIM - Gene 191170
OMIM - Diseases ADCC (Adrenocortical carcinoma, pediatric)
BCC7 (Basal cell carcinoma 7)
BMFS5 (Bone marrow failure syndrome 5)
BrCa (Breast Cancer)
CPP (Choroid plexus papilloma)
CRC (Colorectal cancer)
GLM1 (Glioma susceptibility 1)
LFS (Li-Fraumeni syndrome)
OSRC (Osteosarcoma)


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000213 17 transcript variant 1 NM_000546.5 NP_000537.3 134
00000214 17 transcript variant 1 NM_001276760.1 NP_001263689.1 134
00000215 17 transcript variant 2 NM_001126112.2 NP_001119584.1 134
00000216 17 transcript variant 2 NM_001276761.1 NP_001263690.1 134
00000217 17 transcript variant 3 NM_001126114.2 NP_001119586.1 134
00000218 17 transcript variant 3 NM_001276696.1 NP_001263625.1 134
00000219 17 transcript variant 4 NM_001126113.2 NP_001119585.1 134
00000220 17 transcript variant 4 NM_001276695.1 NP_001263624.1 134
00000221 17 transcript variant 5 NM_001126115.1 NP_001119587.1 134
00000222 17 transcript variant 5 NM_001276697.1 NP_001263626.1 134
00000223 17 transcript variant 6 NM_001126116.1 NP_001119588.1 134
00000224 17 transcript variant 6 NM_001276698.1 NP_001263627.1 134
00000225 17 transcript variant 7 NM_001126117.1 NP_001119589.1 134
00000226 17 transcript variant 7 NM_001276699.1 NP_001263628.1 134
00000227 17 transcript variant 8 NM_001126118.1 NP_001119590.1 134


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