APC gene homepage - CanVaS - A Greek Cancer Patient Genetic Variation Resource

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CanVaS - A Greek Cancer Patient Genetic Variation Resource

APC (APC regulator of WNT signaling pathway)

LOVD v.3.0 Build 23 [ Current LOVD status ]
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	Curator: Despoina Kalfakakou

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APC gene homepage

General information
Gene symbol	APC
Gene name	APC regulator of WNT signaling pathway
Chromosome	5
Chromosomal band	q22.2
Imprinted	Unknown
Genomic reference	LRG_130
Transcript reference	NM_000038.5, NM_001127510.2, NM_001127511.2
Associated with diseases	FAP1
Citation reference(s)	-
Curators (1)	Despoina Kalfakakou
Total number of public variants reported	594
Unique public DNA variants reported	178
Individuals with public variants	587
Hidden variants	0
Date created	May 20, 2020
Date last updated	May 16, 2022
Version	APC:220516

Graphical displays and utilities
Graphs	Graphs displaying summary information of all variants in the database »
UCSC Genome Browser	Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser	Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer	Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC	583
Entrez Gene	324
PubMed articles	APC
OMIM - Gene	611731
OMIM - Diseases	FAP1 (Familial Adenomatous Polyposis 1)

Active transcripts

Legend

Please note that a short description of a certain column can be displayed when you move your mouse cursor over the column's header and hold it still. Below, a more detailed description is shown per column.

ID	Chr	Name	NCBI ID	NCBI Protein ID	Variants
00000005	5	adenomatous polyposis coli, transcript variant 3	NM_000038.5	NP_000029.2	594
00000003	5	adenomatous polyposis coli, transcript variant 1	NM_001127511.2	NP_001120983.2	593
00000004	5	adenomatous polyposis coli, transcript variant 2	NM_001127510.2	NP_001120982.1	593

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