APC gene homepage

General information
Gene symbol APC
Gene name APC regulator of WNT signaling pathway
Chromosome 5
Chromosomal band q22.2
Imprinted Unknown
Genomic reference LRG_130
Transcript reference NM_000038.5, NM_001127510.2, NM_001127511.2
Associated with diseases FAP1
Citation reference(s) -
Curators (1) Despoina Kalfakakou
Total number of public variants reported 594
Unique public DNA variants reported 178
Individuals with public variants 587
Hidden variants 0
Date created May 20, 2020
Date last updated May 16, 2022
Version APC:220516

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 583
Entrez Gene 324
PubMed articles APC
OMIM - Gene 611731
OMIM - Diseases FAP1 (Familial Adenomatous Polyposis 1)

Active transcripts




NCBI ID     

NCBI Protein ID     

00000005 5 adenomatous polyposis coli, transcript variant 3 NM_000038.5 NP_000029.2 594
00000003 5 adenomatous polyposis coli, transcript variant 1 NM_001127511.2 NP_001120983.2 593
00000004 5 adenomatous polyposis coli, transcript variant 2 NM_001127510.2 NP_001120982.1 593

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